Would you like to know what immune-response you develop following the Covid-19 vaccine? Royal Stoke University Hospital have invited volunteers to take part in a research study.

They are looking to recruit 80 people to take part in this study, who fall into these two groups:

Study Group – 50 people who have a suppressed immune system because of a blood disorder or the medicine they have taken for their blood disorders

Control Group – 30 people who have a normal immune system

Why is the study needed?

Covid-19 vaccines are approved for use in people with a suppressed immune system, but no studies have been done to assess what immune response they will have after the vaccination

This study will look into the immune response in people after having a Covid-19 vaccine and will compare it between people with suppressed immunity with those who have normal immunity.

What would be involved?

If you haven't yet had the 1st dose of a Covid-19 vaccine, have an appointment for the 1st dose, or have received the 1st dose the last 10 days, please contact the hospital if you wish to participate. We will send you an information leaflet with more details, and:

- You will be invited to a screening appointment at Royal Stoke Hospital and to have a blood test to see if you already have the Covid-19 antibodies (result must be negative)

- If you meet the criteria for participation in the study, over the next 4 months you will be required to;

- Attend the hospital for 5 follow-up blood tests

- Report any side effects following Covid-19 vaccination by maintaining a symptom diary

This study does not provide you with Covid-19 vaccination. You will receive the Covid-19 vaccine as per Government guidance and priority list.

If you think you might be suitable for this study or would like more information, please contact the study team on 01782 672699 or [email protected]